Abstract
WHILE investigating the effect of abdominal vagotomy on satiety elicited by cholecystokinin1, we noted that many vagotomised rats seemed to be undernourished and failed to regain their preoperative weight. Because of their low water–food ratio (vagotomised 1.3±0.5 ml g−1, sham 1.8±0.1 ml g−1, P<0.001), we analysed their drinking behaviour in various conditions. We report here that abdominal vagotomy produces severe deficits in drinking behaviour that can be characterised as motivational.
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KRALY, F., GIBBS, J. & SMITH, G. Disordered drinking after abdominal vagotomy in rats. Nature 258, 226–228 (1975). https://doi.org/10.1038/258226a0
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DOI: https://doi.org/10.1038/258226a0
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