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X-ray diffraction study of molecular structure and conformation of mezerein

Nature volume 257, pages 824–825 (1975)Cite this article

Abstract

THE crystal structure of one of the toxic components of the plant Daphne mezereum, mezerein, has been solved, unequivocally showing the molecular conformation in the solid state. Extracts from this plant have long been known to contain curative components, and have been used extensively in folk medicine in several countries1. Mezerein has attracted attention for its anti-leukaemic activity against P-388 and P-1210 leukaemias in mice2.

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Authors and Affiliations

  1. Department of Chemistry, University of Aarhus, 8000, Aarhus C, Denmark

    JENS NYBORG & TROELS LA COUR

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  1. JENS NYBORG
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  2. TROELS LA COUR
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NYBORG, J., COUR, T. X-ray diffraction study of molecular structure and conformation of mezerein. Nature 257, 824–825 (1975). https://doi.org/10.1038/257824a0

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  • DOI: https://doi.org/10.1038/257824a0

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