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Reassembly of a spherical virus in mild conditions

Nature volume 255, pages 737–738 (1975)Cite this article

Abstract

ALTHOUGH successful reassembly of a number of spherical viruses has been reported1–5, this has hitherto only been accomplished in conditions which are clearly non-physiological. We now report the reassembly of cowpea chlorotic mottle virus (CCMV) in mild conditions, ∼pH 6, ionic strength 0.1 or 0.2 and 20 to 25 °C; conditions which are plausible for an in vivo assembly reaction.

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Authors and Affiliations

  1. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK

    K. W. ADOLPH & P. J. G. BUTLER

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  1. K. W. ADOLPH
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  2. P. J. G. BUTLER
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ADOLPH, K., BUTLER, P. Reassembly of a spherical virus in mild conditions. Nature 255, 737–738 (1975). https://doi.org/10.1038/255737a0

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  • DOI: https://doi.org/10.1038/255737a0

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