Abstract
FROG slow muscle fibres are usually unable to generate action potentials1,2. It has been demonstrated, however, that this ability is acquired after denervation3,4, and it has been suggested that the inhibitory effect of the small motor axons on the slow fibre membrane results from the release of a ‘trophic’ substance4–6. Since slow muscle fibres are usually innervated by more than one motor axon1, it was important to find out, whether the action potential is induced after partial removal of this ‘trophic’ influence. Our results show that this is indeed the case.
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SCHALOW, G., SCHMIDT, H. Action potentials induced in slow muscle fibres by partial denervation. Nature 253, 122–123 (1975). https://doi.org/10.1038/253122a0
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DOI: https://doi.org/10.1038/253122a0
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