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Marijuana metabolites measured by a radioimmune technique

Abstract

THE recent surge of interest in the pharmacology of cannabinoids has created a need for a rapid assay for Δ9-tetrahydrocannabinol (Δ9-THC) and its metabolites in body fluids. A sensitive immune technique has proved elusive, and quantitation requires a multistep chromatographic and mass spectroscopic analysis1. Gas liquid chromatography with electron capture detection has also been used2,3. We describe here a simple rapid radio-immune assay for Δ9-THC utilising goat antiserum obtained as previously described4.

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GROSS, S., SOARES, J., WONG, SL. et al. Marijuana metabolites measured by a radioimmune technique. Nature 252, 581–582 (1974). https://doi.org/10.1038/252581a0

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