Abstract
THE specificity of receptors on thymus-derived cells (T) and bone marrow-derived cells (B) for the same antigen is of interest if the various immune responses directed towards protein antigens1 are to be understood. Detailed molecular studies of such specificities can only be undertaken with protein antigens of known structure. Following a large body of detailed work on the antigenic structure of cytochrome c for determinants related to antibodies2, we report here the beginnings of a similar approach to an analysis of the determinants in cytochrome c related to delayed hypersensitivity.
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REICHLIN, M., TURK, J. Specificity of antigen receptors for cytochrome c in delayed hypersensitivity. Nature 251, 355–356 (1974). https://doi.org/10.1038/251355a0
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DOI: https://doi.org/10.1038/251355a0
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