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Nitrosoguanidine mutagenesis during nuclear and mitochondrial gene replication

A Corrigendum to this article was published on 11 October 1974

Abstract

The timing of individual nuclear gene replication during S phase in an eukaryote can now be studied by nitrosoguanidine mutagenesis. Using this technique, results also suggested that mitochondrial DNA replication is synchronous and a late event in the cell cycle.

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Dawes, I., Carter, B. Nitrosoguanidine mutagenesis during nuclear and mitochondrial gene replication. Nature 250, 709–712 (1974). https://doi.org/10.1038/250709a0

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