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Y chromosome effect on adult testis size

Abstract

DURING the development of mammals with X and Y chromosomes the Y chromosome brings about the differentiation of the gonad primordia into testes1. But apart from carrying the genetic determinants of maleness, little is known about its genetic constitution. In man, the gene for hairy tips to the ears shows Y linkage in at least some pedigrees2. In mice there is evidence for a Y-linked histocompatibility locus3,4, and for effects of the Y chromosome on the frequency of spermatozoa with abnormal heads5. Here we show that the size of the testes of adult mice is affected by factors on the Y chromosome.

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HAYWARD, P., SHIRE, J. Y chromosome effect on adult testis size. Nature 250, 499–500 (1974). https://doi.org/10.1038/250499a0

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