Abstract
The evidence that rabbit DTNB light chains bind to ‘desensitised’ scallop myosin and restore calcium sensitivity, that is, they functionally replace the scallop EDTA light chain, may suggest that these light chains are involved in some type of calcium regulatory mechanism in rabbit myosin in vivo.
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References
Ebashi, S., Endo, M., and Ohtsuki, I., Q. Rev. Biophys., 2, 351 (1969).
Kendrick-Jones, J., Lehman, W., and Szent-Györgyi, A. G., J. molec. Biol., 54, 313 (1970).
Lehman, W., Kendrick-Jones, J., and Szent-Györgyi, A. G., Cold Spring Harbor Symp. quant. Biol., 37, 319 (1972).
Szent-Györgyi, A. G., Szentkiralyi, E. M., and Kendrick-Jones, J., J. molec. Biol., 74, 179 (1973).
Locker, R. H., and Hagyard, C. J., Archs Biochem. Biophys., 122, 521 (1967).
Gaetjens, E., Bárány, K., Bailin, G., Oppenheimer, H., and Bárány, M., Archs Biochem. Biophys., 123, 82 (1968).
Gazith, J., Himmelfarb, S., and Harrington, W. F., J. biol. Chem., 245, 15 (1970).
Samaha, F. J., Guth, L., and Albers, R. W., J. biol. Chem., 245, 219 (1970).
Perrie, W. T., and Perry, S. V., Biochem. J., 119, 31 (1970).
Lowey, S., and Risby, D., Nature, 234, 81 (1971).
Sarkar, S., Sreter, F. A., and Gergely, J., Proc. natn. Acad. Sci. U.S.A., 68, 946 (1971).
Weeds, A. G., and Pope, B., Nature, 234, 85 (1971).
Kendrick-Jones, J., Phil. Trans. R. Soc. Lond., B 265, 183 (1973).
Weeds, A. G., and Lowey, S., J. molec. Biol., 61, 701 (1971).
Weeds, A. G., Nature, 223, 1362 (1969).
Weeds, A. G., and Frank, G., Cold Spring Harbor Symp. quant. Biol., 37, 9 (1972).
Stracher, A., Biochem. biophys. Res. Commun., 35, 519 (1969).
Dreizen, P., and Gershman, L. C., Biochemistry, 9, 1688 (1970).
Lowey, S., Slayter, H. S., Weeds, A. G., and Baker, H., J. molec. Biol., 42, 1 (1969).
Eisenberg, E., Zobel, C. R., and Moos, C., Biochemistry, 7, 3186 (1968).
Kendrick-Jones, J., Szentkiralyi, E. M., and Szent-Györgyi, A. G., Cold Spring Harbor Symp. quant. Biol., 37, 47 (1972).
Gershman, L. C., Stracher, A., and Dreizen, P., J. biol. Chem., 244, 2726 (1969).
Bray, D., and Brownlee, S. M., Analyt. Biochem., 55, 213 (1973).
Bremel, R. D., and Weber, A., Nature, 238, 97 (1972).
Haselgrove, J. C., thesis, Univ. Cambridge. (1970).
Huxley, H. E., Cold Spring Harbor Symp. quant. Biol., 37, 361 (1972).
Weber, A., and Murray, J. M., Physiol. Rev., 53, 612 (1973).
Perrie, W. T., Smillie, L. B., and Perry, S. V., Biochem. J., 135, (1973).
Weber, K., and Osborn, M., J. biol. Chem., 244, 4406 (1969).
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Kendrick-Jones, J. Role of myosin light chains in calcium regulation. Nature 249, 631–634 (1974). https://doi.org/10.1038/249631a0
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DOI: https://doi.org/10.1038/249631a0
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