Abstract
IN a recent publication1, Elleman, Lindley and Rowlands claimed that there is no evidence to support the view that high-sulphur proteins from wool have a common ancestral protein partly composed of a repeating unit of five amino acids2,3. Their evidence for a repeating decapeptide unit is restricted almost entirely to the region between residues 22 and 64 of protein SCMKB2B. Although the C terminal region of this sequence shows some correlation to the repeating decapeptide unit, it correlates better with a pentapeptide repeating unit as shown previously (ref. 3).
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References
Elleman, T. C., Lindley, H., and Rowlands, R. J., Nature, 246, 530 (1973).
Ycas, M., J. molec. Evol., 2, 17 (1972).
Swart, L. S., Nature new Biol., 243, 27 (1973).
Elleman, T. C., Biochem. J., 130, 833 (1972).
Dayhoff, M. O., Atlas of Protein Sequence and Structure (National Biomedical Research Foundation, Silver Spring, Maryland, 1972).
Lindley, H., and Elleman, T. C., Biochem. J., 128, 859 (1972).
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SWART, L., PARRIS, D. Periodicity in high sulphur proteins from wool. Nature 249, 580–581 (1974). https://doi.org/10.1038/249580a0
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DOI: https://doi.org/10.1038/249580a0
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