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Immunisation of marmoset monkeys with a killed oncogenic herpesvirus

Nature volume 249, pages 571–572 (1974)Cite this article

Abstract

HERPESVIRUSES are suspected to be causal agents in human malignant neoplasia. At the present level of knowledge, clinical trials in man with viral vaccines against oncogenic herpesviruses cannot be initiated, but the oncogenic herpesviruses derived from monkeys1,2 can be used in vivo to study the problems of herpesvirus cancer vaccines. The oncogenic herpesvirus saimiri (HVS) regularly induces malignant lymphoma in cotton topped (CT) marmoset monkeys (S. oedipus). A killed vaccine from HVS was developed in our laboratory and tested for safety and efficacy in this primate model system.

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References

  1. Meléndez, L. V., Hunt, R. D., Daniel, M. D., Garcia, F. G., and Fraser, C. E. O., Lab. Anim. Care, 19, 378 (1969).

    PubMed  Google Scholar 

  2. Laufs, R., and Meléndez, L. V., J. natn. Cancer Inst., 51, 599 (1973).

    CAS  Google Scholar 

  3. Laufs, R., and Meléndez, L. V., Med. Microbiol. Immun., 158, 299 (1973).

    Article  CAS  Google Scholar 

  4. Lennette, E. H., and Schmidt, N. J., Diagnostic Procedures for Viral and Rickettsial Diseases (American Public Health Association, New York, 1964).

    Google Scholar 

  5. Ablashi, D. V., Loeb, W. F., Pearson, G., Valerio, M. G., Armstrong, G. R., Rabin, H., Kingsbury, E. W., and Heine, U., Nature new Biol., 242, 28 (1973).

    Article  CAS  Google Scholar 

  6. Duff, R., and Rapp, F., J. Virol., 8, 469 (1971).

    CAS  PubMed  PubMed Central  Google Scholar 

  7. Rapp, F., Li, J. H., and Jerkofsky, M., Virology, 55, 339 (1973).

    Article  CAS  Google Scholar 

  8. Shope, T., Dechairo, D., and Miller, G., Proc. natn. Acad. Sci. U.S.A., 70, 2487 (1973).

    Article  ADS  CAS  Google Scholar 

  9. Epstein, M. A., Hunt, R. D., and Rabin, H., Int. J. Cancer, 12, 309 (1973).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Hygiene-Institut der Universität, Göttingen, D-34, West Germany

    R. LAUFS

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  1. R. LAUFS
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LAUFS, R. Immunisation of marmoset monkeys with a killed oncogenic herpesvirus. Nature 249, 571–572 (1974). https://doi.org/10.1038/249571a0

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  • DOI: https://doi.org/10.1038/249571a0

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