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Mechanisms of sensing chemical gradients by polymorphonuclear leukocytes

Nature volume 249, pages 450–452 (1974)Cite this article

Abstract

ALTHOUGH it has been known for nearly 100 yr that polymorphonuclear leukocytes (PMNs) can show oriented locomotion in response to chemical gradients, that is, they display chemotaxis, the way in which these cells detect and respond to chemical gradients is still not understood1. These questions are of interest, not only to a study of the inflammatory process, but also to more general problems of oriented cell movements during morphogenesis.

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Author notes

  1. SALLY H. ZIGMOND

    Present address: Section of Cell Biology, Yale Medical School, New Haven, Connecticut

Authors and Affiliations

  1. Strangeways Research Laboratory, Cambridge, UK

    SALLY H. ZIGMOND

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  1. SALLY H. ZIGMOND
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ZIGMOND, S. Mechanisms of sensing chemical gradients by polymorphonuclear leukocytes. Nature 249, 450–452 (1974). https://doi.org/10.1038/249450a0

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