Abstract
THE properties and activities of mammalian cell membranes have become an area of increasing interest in cell biology, and their study has involved a variety of experimental approaches. The mutual interaction of membranes from identical or different cell types has often been studied. For example, it has been found that a large proportion of human peripheral blood lymphocytes, when mixed with sheep red blood cells, form cell clusters known as rosettes, in which a central tymphocyte is partially or fully surrounded by red cells1–3. This also occurs with human thymocytes4, and is apparently a property of human lymphocytes derived from the thymus (T cells)5,6.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Brain, P., Gordon, J., and Willetts, W. A., Clin. exp. Immun., 6, 681 (1970).
Lay, W. H., Mendes, N. F., Bianco, C., and Nussenzweig, V., Nature, 230, 531 (1971).
Coombs, R. R. A., Gurner, B. W., Wilson, A. B., Holm, G., and Lindgren, B., Int. Archs Allergy, 39, 658 (1970).
Nussenzweig, V., in Cell Interactions and Receptor Antibodies in Immune Responses (edit. by Mäkelä, O., and Kosunen, T. U., 449 (Academic, New York and London, 1971).
Fröland, S. G., Scand. J. Immun., 1, 269 (1972).
Jondal, M., Holm, G., and Wigzell, H., J. exp. Med., 136, 207 (1972).
Tønder, O., and Thunold, S., Scand. J. Immun., 2, 207 (1973).
Littlefield, J. W., Proc. natn. Acad. Sci., U.S.A. 50, 568 (1963).
Connors, T. A., and Jones, M., Recent Results Cancer Res., 33, 181 (1970).
Davidson, R., Expl. Cell Res., 55, 424 (1969).
Phillips, B. J., and Ambrose, E. J., Nature new Biol., 231, 146 (1971).
Yoshida, T. O., and Andersson, B., Scand. J. Immun., 1, 401 (1972).
Haskill, J. S., Elliott, B. E., Kerbel, R., Axelrad, M. A., and Eidinger, D., J. exp. Med., 135, 1410 (1972).
Elliott, B. E., and Haskill, J. S., Eur. J. Immun., 3, 68 (1973).
Wybran, J., and Fudenberg, H. H., J. clin. Invest., 52, 1026 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ELLIOTT, E., KERBEL, R. & PHILLIPS, B. Rosette formation by a mouse fibroblast cell line. Nature 248, 514–515 (1974). https://doi.org/10.1038/248514a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/248514a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.