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Effect of 5-fluorouracil on the gibberellic acid-induced formation of thermolabile α-amylase molecules in barley aleurone cells

Abstract

IN the aleurone cells of barley seed gibberellic acid (GA) stimulates de novo synthesis of α-amylase1,2. From a study of the effect of 5-fluorouracil (FU) on the GA-evoked formation of thermolabile α-amylase molecules, Carlson3 has concluded that GA regulates a post-transcriptional control point. According to my interpretation, which differs from Carlson's conclusion, his data (Fig. 1, ref. 3) suggest that mRNAs for α-amylase are formed in the presence of GA.

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CHANDRA, G. Effect of 5-fluorouracil on the gibberellic acid-induced formation of thermolabile α-amylase molecules in barley aleurone cells. Nature 248, 161–162 (1974). https://doi.org/10.1038/248161a0

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