Abstract
The evolution of enzymes in bacteria is studied by introducing novel substrates and selecting strains that have mutated to be able to use these substrates.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Dagley, S., in Degradation of Synthetic Organic Molecules in the Biosphere (Natn. Acad. Sci., Washington, 1972).
Brown, J. E., Brown, P. R., and Clarke, P. H., J. gen. Microbiol., 57, 273 (1969).
Brown, P. R., and Clarke, P. H., J. gen. Microbiol., 70, 287 (1972).
Betz, J. L., and Clarke, P. H., J. gen. Microbiol., 73, 161 (1972).
Clarke, P. H., J. gen. Microbiol., 71, 241 (1972).
Wood, W. A., A. Rev. Biochem., 35, 521 (1966).
LeBlanc, D. J., and Mortlock, R. P., J. Bact., 106, 90 (1971).
Zamenhof, S., and Eichhorn, H. H., Nature, 216, 456 (1967).
Oliver, E. J., and Mortlock, R. P., J. Bact., 108, 293 (1971).
Wu, T. T., Lin, E. C. C., and Tanaka, S., J. Bact., 96, 447 (1968).
Brown, P. R., Smyth, M. J., Clarke, P. H., and Rosemeyer, M. A., Eur. J. Biochem., 34, 177 (1973).
Brammar, W. J., and Clarke, P. H., J. gen. Microbiol., 37, 307 (1964).
Brammar, W. J., Clarke, P. H., and Skinner, A. J., J. gen. Microbiol., 47, 87 (1967).
Brown, J. E., and Clarke, P. H., J. gen. Microbiol., 64, 329 (1970).
Betz, J. L., and Clarke, P. H., J. gen. Microbiol., 75, 167 (1973).
Ohno, S., Evolution by Gene Duplication (Allen and Unwin, London, 1970).
Koch, A. L., Genetics, 72, 297 (1972).
Rheinwald, J. G., Chakrabarty, A. M., and Gunsalus, I. C., Proc. natn. Acad. Sci. U.S.A., 70, 885 (1973).
Chakrabarty, A. M., Chou, G., and Gunsalus, I. C., Proc. natn. Acad. Sci. U.S.A., 70, 1137 (1973).
Chakrabarty, A. M., J. Bact., 112, 815 (1972).
Dunn, N. W., and Gunsalus, I. C., J. Bact., 114, 974 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Betz, J., Brown, P., Smyth, M. et al. Evolution in Action. Nature 247, 261–264 (1974). https://doi.org/10.1038/247261a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/247261a0
This article is cited by
-
The Experimental Study of Bacterial Evolution and Its Implications for the Modern Synthesis of Evolutionary Biology
Journal of the History of Biology (2018)
-
Role of Biotechnology in the Treatment of Polyester Fabric
Indian Journal of Microbiology (2011)
-
In vivo versus in vitro screening or selection for catalytic activity in enzymes and abzymes
Molecular Biotechnology (1997)
-
Genetic aspects of toxic chemical degradation
Microbial Ecology (1986)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.