Abstract
A balance defect seen in a histidinaemic strain of mouse “segregates” abnormally, suggesting teratogenic effects of maternal metabolism. This effect may be analogous to certain human disorders.
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References
Raine, D. N., Cooke, J. R., Andrews, W. A., and Mahon, D. F., Brit. Med. J., 3, 7 (1972).
Lott, I. T., Wheelden, J. A., and Levy, H. L., Develop. Med. Child. Neurol., 12, 596 (1970).
Wallace, M. E., Mouse News Lett., 42, 20 (1970).
Wallace, M. E., Environ. Pollut., 1, 175 (1971).
Coleman, D. L., Arch. Biochem. Biophys., 96, 562 (1962).
Harris, H., The Principles of Human Biochemical Genetics (North-Holland, Amsterdam and London, 1970).
Paigen, K., in Enzyme Synthesis and Degradation in Mammalian Systems (edit. by Rechigl, M.) (Karger, Basel, 1971).
Bulfield, G., Genet. Res., 20, 51 (1972).
Noda, K., and Nakagawa, H., Endocrinology, 90, 207 (1972).
Kacser, H., and Burns, J., Quantitative Biology of Metabolism, 11 (Third International Symposium, Biologische Anstalt Helgoland, 1968).
Kacser, H., and Burns, J., in Symp. Soc. Exp. Biol., 27, 65 (1973).
Wallace, M. E., Mouse Newsletter, 48, 25 (1973).
Sidman, R. L., Green, M. C., and Appel, S. H., Catalog of the Neurological Mutants of the Mouse (Harvard University Press, Cambridge, Massachusetts, 1965).
Lyon, M. F., Genet. Res., 1, 189 (1960).
Chai, C. K., and Chiang, M. S. M., Genetics, 47, 435 (1962).
Auerbach, V. H., DiGeorge, A. M., Baldridge, R. C., Tourtellotte, C. D., and Brigham, M. P., J. Pediat., 60, 487 (1962).
Neville, B. G. R., Bentovim, A., Clayton, B. E., and Shepherd, J., Arch. Dis. Child., 47, 190 (1972).
Wadman, S. K., De Bree, P. K., Van der Heiden, C., and Van Sprang, F. J., Clin. Chim. Acta, 31, 215 (1971).
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KACSER, H., BULFIELD, G. & WALLACE, M. Histidinaemic Mutant in the Mouse. Nature 244, 77–79 (1973). https://doi.org/10.1038/244077a0
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DOI: https://doi.org/10.1038/244077a0
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