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Relation between Apatite Solubility and Anti-cariogenic Effect of Fluoride

Nature volume 243, pages 420–421 (1973)Cite this article

Abstract

THE free enthalpy of formation of solid solutions of hydroxyapatite (OHA) and fluorapatite (FA) at 25° C has been determined1. I have used these thermodynamical data to calculate (Driessens, unpublished) the solubility of the solid solutions in aqueous solutions at certain pH values. For this purpose, the following relations were derived: where subscript (s) means that the preceding molecular unit is part of the solid solution; subscript (1) means that the preceding ion is dissolved in the aqueous solution; K1OHA and K1FA are the apparent solubility products of the components OHA and FA over the solid solution respectively: they depend on x; KOHA and KFA are the solubility products of pure OHA and pure FA respectively: they are independent of x; aOHA and aFA are the thermodynamical activities of FA and OHA, which are sufficient to account for the dependence on x.

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References

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Authors and Affiliations

  1. Institute of Dental Materials, Science and Technology, University of Nijmegen Erasmuslaan, 1, Nijmegen

    F. C. M. DRIESSENS

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  1. F. C. M. DRIESSENS
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DRIESSENS, F. Relation between Apatite Solubility and Anti-cariogenic Effect of Fluoride. Nature 243, 420–421 (1973). https://doi.org/10.1038/243420a0

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  • DOI: https://doi.org/10.1038/243420a0

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