Abstract
GAL1 has suggested that hormonal pregnancy tests may be teratogenic to the developing central nervous system. In a study of 100 mothers of spina bifida cases she found nineteen of these mothers had had a hormonal pregnancy test (‘Amenorone Forte’ or ‘Primodos’) compared with four of 100 “matched” control mothers. Laurence2 has criticized Gal's findings on two counts: (1) the choice of controls, and (2) the possibility of finding a difference this great by chance when a number of epidemiologic factors are studied.
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References
Gal, I., Nature, 240, 241 (1972).
Laurence, K. M., Nature, 240, 242 (1972).
Lemire, R. J., Teratology, 2, 361 (1969).
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SEVER, L. Hormonal Pregnancy Tests and Spina Bifida. Nature 242, 410–411 (1973). https://doi.org/10.1038/242410a0
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DOI: https://doi.org/10.1038/242410a0
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