Abstract
AFTER division of a sympathetic nerve, reinnervation occurs by growth of axons from neurones located in the sympathetic ganglia. These ganglia survive in artificial media, and the neurones continue to respond to acetylcholine for more than 1 week after their isolation in vitro1. A rat iris placed in contact with a superior cervical ganglion in organ culture is ramified by nerve fibres emanating from the ganglion cell bodies2. The catecholamine histochemical method has shown that nerve fibres begin to enter the iris from the ganglion as early as the second day in culture in the presence of exogenous nerve growth factor2.
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SILBERSTEIN, S., BERV, K. & JACOBOWITZ, D. Heterologous Reinnervation of the Iris from Sympathetic Ganglia in Organ Culture. Nature 239, 466–468 (1972). https://doi.org/10.1038/239466a0
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DOI: https://doi.org/10.1038/239466a0
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