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Natural Selection and Genetic Drift in Protein Polymorphism

Nature volume 239, pages 160–161 (1972)Cite this article

Abstract

THE Kimura theory1 that protein polymorphism is mainly due to random genetic drift acting on a number of neutral isoalleles has been recently discussed by many authors2–4. The electrophoretic study of populations of the same species having different geographical origin and showing great fluctuations in number offers possibilities for testing the relative importance of natural selection and genetic drift in the context. We report a study of two species of mosquitoes, Aedes aegypti and Aedes mariae, for the phosphoglucomutase (PGM) locus. This is an autosomal locus belonging in A. aegypti to the linkage group 2 and showing in both species a very high number of electrophoretically detectable alleles (Bullini et al., refs. 5 and 6, and unpublished data).

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References

  1. Kimura, M., Nature, 217, 624 (1968).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Prakash, S., Lewontin, R. C., and Hubby, J. L., Genetics, 61, 841 (1969).

    CAS  PubMed  PubMed Central  Google Scholar 

  3. Kimura, M., and Ohta, T., Nature, 229, 467 (1971).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Bulmer, M. G., Nature, 234, 410 (1971).

    Article  ADS  CAS  PubMed  Google Scholar 

  5. Bullini, L., Coluzzi, M., Gironi, A. M., and Morellini, M., Parassitologia, 12, 27 (1970).

    Google Scholar 

  6. Bullini, L., Gironi, A. M., Bianchi Bullini, A. P., and Coluzzi, M., Biochemical Genetics (in the press).

  7. Coluzzi, M., and Bullini, L., Nature, 231, 455 (1971).

    Article  ADS  CAS  PubMed  Google Scholar 

  8. Coluzzi, M., Bullini, L., and Bianchi Bullini, A. P., Biochemical Genetics, 5, 253 (1971).

    Article  CAS  PubMed  Google Scholar 

  9. Coluzzi, M., Bullini, L., and Bianchi Bullini, A. P., Bull. Ent. Res., 61, 327 (1971).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Istituto di Genetica, Universitá di Roma,

    LUCIANO BULLINI

  2. Istituto di Parassitologia, Universitá di Roma,

    MARIO COLUZZI

Authors
  1. LUCIANO BULLINI
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  2. MARIO COLUZZI
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BULLINI, L., COLUZZI, M. Natural Selection and Genetic Drift in Protein Polymorphism. Nature 239, 160–161 (1972). https://doi.org/10.1038/239160a0

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