Abstract
Three-dimensional image reconstruction shows haemocyanin to be made of three distinct parts. At the ends of the particle are a five-fold “collar” and a central “cap”. The cylindrical wall consists of sixty dimers which may be correlated with 120 oxygen binding sites.
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References
New Developments in Electron Microscopy (edit. by Huxley, H. E., and Klug, A.) (Royal Society, London, 1971).
Physiology and Biochemistry of Haemocyanins (edit. by Ghiretti, F.) (Academic Press, New York, 1968).
Ericksson-Quensel, I., and Svedberg, T., Biol. Bull., 71, 498 (1936).
van Holde, K. E., and Cohen, L. B., Biochemistry, 3, 1803 (1964).
van Bruggen, E. F. J., Wiebenga, E. H., and Gruber, M., J. Mol. Biol., 4, 1 (1962).
Fernández-Morán, H., van Bruggen, E. F. J., and Ohtsuki, M., J. Mol. Biol., 16, 191 (1966).
DeRosier, D. J., and Klug, A., Nature, 217, 130 (1968).
Condie, R. M., and Langer, R. B., Science, 144, 1138 (1964).
Eskeland, T. J., Ultrastruct. Res., 17, 544 (1967).
Crowther, R. A., and Amos, L. A., J. Mol. Biol., 60, 123 (1971).
DeRosier, D. J., and Moore, P. B., J. Mol. Biol., 52, 355 (1970).
van Holde, K. E., in Molecular Architecture and Cell Physiology (edit. by Hayashi, T., and Szent-Györgyi, A. G.) (Prentice-Hall, Englewood Cliffs, New Jersey, 1966).
Caspar, D. L. D., in Molecular Architecture and Cell Physiology (edit. by Hayashi, T., and Szent-Györgyi, A. G.) (Prentice-Hall, Englewood Cliffs, New Jersey, 1966).
King, J., J. Mol. Biol., 32, 231 (1968).
Klug, A., Crick, F. H. C., and Wyckoff, H. W., Acta Cryst., 11, 199 (1958).
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MELLEMA, J., KLUG, A. Quaternary Structure of Gastropod Haemocyanin. Nature 239, 146–150 (1972). https://doi.org/10.1038/239146a0
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DOI: https://doi.org/10.1038/239146a0
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