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Quaternary Structure of Gastropod Haemocyanin

Abstract

Three-dimensional image reconstruction shows haemocyanin to be made of three distinct parts. At the ends of the particle are a five-fold “collar” and a central “cap”. The cylindrical wall consists of sixty dimers which may be correlated with 120 oxygen binding sites.

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References

  1. New Developments in Electron Microscopy (edit. by Huxley, H. E., and Klug, A.) (Royal Society, London, 1971).

  2. Physiology and Biochemistry of Haemocyanins (edit. by Ghiretti, F.) (Academic Press, New York, 1968).

  3. Ericksson-Quensel, I., and Svedberg, T., Biol. Bull., 71, 498 (1936).

    Article  Google Scholar 

  4. van Holde, K. E., and Cohen, L. B., Biochemistry, 3, 1803 (1964).

    Article  CAS  Google Scholar 

  5. van Bruggen, E. F. J., Wiebenga, E. H., and Gruber, M., J. Mol. Biol., 4, 1 (1962).

    Article  CAS  Google Scholar 

  6. Fernández-Morán, H., van Bruggen, E. F. J., and Ohtsuki, M., J. Mol. Biol., 16, 191 (1966).

    Article  Google Scholar 

  7. DeRosier, D. J., and Klug, A., Nature, 217, 130 (1968).

    Article  ADS  CAS  Google Scholar 

  8. Condie, R. M., and Langer, R. B., Science, 144, 1138 (1964).

    Article  ADS  CAS  Google Scholar 

  9. Eskeland, T. J., Ultrastruct. Res., 17, 544 (1967).

    Article  CAS  Google Scholar 

  10. Crowther, R. A., and Amos, L. A., J. Mol. Biol., 60, 123 (1971).

    Article  CAS  Google Scholar 

  11. DeRosier, D. J., and Moore, P. B., J. Mol. Biol., 52, 355 (1970).

    Article  CAS  Google Scholar 

  12. van Holde, K. E., in Molecular Architecture and Cell Physiology (edit. by Hayashi, T., and Szent-Györgyi, A. G.) (Prentice-Hall, Englewood Cliffs, New Jersey, 1966).

    Google Scholar 

  13. Caspar, D. L. D., in Molecular Architecture and Cell Physiology (edit. by Hayashi, T., and Szent-Györgyi, A. G.) (Prentice-Hall, Englewood Cliffs, New Jersey, 1966).

    Google Scholar 

  14. King, J., J. Mol. Biol., 32, 231 (1968).

    Article  CAS  Google Scholar 

  15. Klug, A., Crick, F. H. C., and Wyckoff, H. W., Acta Cryst., 11, 199 (1958).

    Article  CAS  Google Scholar 

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MELLEMA, J., KLUG, A. Quaternary Structure of Gastropod Haemocyanin. Nature 239, 146–150 (1972). https://doi.org/10.1038/239146a0

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