Abstract
OHNO1–3 has suggested that during mammalian evolution tetraploidy occurred with a resultant doubling of the chromosome number and DNA content, from 2–3 × 108 yr ago1–4. The recent technique of chromosome banding, through the use of quinacrine fluorescence and giemsa staining; has allowed evidence such as similar pairs of chromosome pairs in the karyotypes of modern mammals to be examined. The following observations are compatible with the existence of modern remnants of ancient tetraploidy.
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COMINGS, D. Evidence for Ancient Tetraploidy and Conservation of Linkage Groups in Mammalian Chromosomes. Nature 238, 455–457 (1972). https://doi.org/10.1038/238455a0
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DOI: https://doi.org/10.1038/238455a0
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