Abstract
MOST diploid cells isolated from animal tissues cannot grow at the suspended state and suspension culture is successful only for established cell lines or tumour cells. It would be interesting to know why primary cells can grow only when stuck on a solid substratum because transformed cells are often distinguished from normal cells by their ability to grow in soft agar suspension1. Such a property may reflect the tendency of malignant cells to be detached from original tissues and to grow freely, as in ascites tumours.
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References
MacPherson, I., and Montagnier, L., Virology, 23, 291 (1964).
Yaoi, Y., and Kanaseki, T., Nature, 237, 283 (1972).
Eagle, H., Science, 130, 432 (1959).
Merchant, D. J., and Hellman, K. B., Proc. Soc. Exp. Biol. Med., 110, 194 (1962).
Yaoi, Y., and Amano, M., J. Gen. Virol., 9, 69 (1970).
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YAOI, Y., ONODA, T. & TAKAHASHI, H. Inhibition of Mitosis in Suspension Culture of Chick Embryo Cells. Nature 237, 285–286 (1972). https://doi.org/10.1038/237285a0
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DOI: https://doi.org/10.1038/237285a0
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