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Molecular Evolution in the Descent of Man

Abstract

Three computer programs applied to data from phylogenetic trees and protein polymorphism can be used to find the rate of molecular evolution of different species. It can be shown that this is slower for higher primates than for other mammals.

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References

  1. Ingram, V. M., Nature, 189, 704 (1961).

    ADS  CAS  PubMed  Google Scholar 

  2. Goodman, M., Human Biol., 33, 131 (1961).

    CAS  PubMed  Google Scholar 

  3. Goodman, M., in Classification and Human Evolution, 203 (Aldine Press, 1963).

    Google Scholar 

  4. Goodman, M., in Protides of Biological Fluids, 70 (Elsevier, Amsterdam, 1965).

    Google Scholar 

  5. Kimura, M., Nature, 217, 624 (1968).

    Article  ADS  CAS  PubMed  Google Scholar 

  6. King, J. L., and Jukes, T. H., Science, 164, 788 (1969).

    ADS  CAS  PubMed  Google Scholar 

  7. Fitch, W. M., and Margoliash, E., Science, 155, 279 (1967).

    Article  ADS  CAS  PubMed  Google Scholar 

  8. Sokal, R., and Sneath, P. H. A., Principles of Numerical Taxonomy, 309 (W. H. Freeman, San Francisco, 1963).

    Google Scholar 

  9. Moore, G. W., thesis, Univ. North Carolina (1970).

  10. Barnabas, J., Goodman, M., and Moore, G. W., Comp. Physiol. Biochem., 39 B, 455 (1971).

    CAS  Google Scholar 

  11. Braun, V., Crichton, R. R., and Braunitzer, G., Z. Physiol. Chem., 349, 45 (1968).

    CAS  Google Scholar 

  12. Braunitzer, G., Buse, G., and Braig, S., Z. Physiol. Chem., 350, 1477 (1969).

    CAS  Google Scholar 

  13. Edmundson, A. B., Nature, 205, 883 (1965).

    Article  ADS  CAS  Google Scholar 

  14. Dayhoff, M. O., Atlas of Protein Sequence and Structure, 4 (1969).

  15. Rudloff, V., Zelenik, M., and Braunitzer, G., Z. Physiol. Chem., 344, 284 (1966).

    CAS  Google Scholar 

  16. Hilse, K., and Braunitzer, G., Z. Physiol. Chem., 349, 433 (1968).

    CAS  Google Scholar 

  17. Matsuda, G., Takei, H., Wu, K. C., Mizuno, K., and Shiozawa, T., Eighth Intern. Cong. Biochemistry, Abstract, 4 (1970).

  18. Von Ehrenstein, G., Cold Spring Harbor Symp. Quant. Biol., 31, 705 (1966).

    CAS  PubMed  Google Scholar 

  19. Hill, R. L., unpublished data taken from Handbook of Biochemistry (The Chemical Rubber Company, 1968).

    Google Scholar 

  20. Rifkin, D. B., Hirsch, D. I., Rifkin, M. R., and Konigsberg, W., Cold Spring Harbor Symp. Quant. Biol., 31, 715 (1966).

    CAS  PubMed  Google Scholar 

  21. Popp, R. A., J. Mol. Biol., 27, 9 (1967).

    CAS  PubMed  Google Scholar 

  22. Matsuda, G., Maita, T., Takei, H., Ota, H., Yamaguchi, M., Miyanchi, T., and Migita, M., J. Biochem. (Japan), 64, 279 (1968).

    CAS  PubMed  Google Scholar 

  23. Zuckerkandl, E., and Schroeder, W. A., Nature, 192, 984 (1961).

    ADS  CAS  Google Scholar 

  24. Rifkin, D. B., and Konigsberg, W., Biochim. Biophys. Acta, 104, 457 (1965).

    CAS  PubMed  Google Scholar 

  25. Braunitzer, G., Gehring-Mueller, R., Hilschmann, N., Hilse, K., Hobom, G., Rudloff, Y., and Wittman-Liebold, B., Z. Physiol. Chem., 325, 283 (1961).

    CAS  Google Scholar 

  26. Schroeder, W. A., Shelton, J. R., Shelton, J. B., and Cormick, J., Biochemistry, 2, 1353 (1963).

    CAS  PubMed  Google Scholar 

  27. Kilmartin, J. V., and Clegg, J. B., Nature, 213, 269 (1967).

    ADS  CAS  PubMed  Google Scholar 

  28. Matsuda, G., Gehring-Mueller, R., and Braunitzer, G., Biochem. Z., 338, 669 (1963).

    CAS  PubMed  Google Scholar 

  29. Schroeder, W. A., Shelton, J. R., Shelton, J. B., Robberson, B., and Babin, D. R., Arch. Biochem. Biophys., 120, 1 (1967).

    CAS  PubMed  Google Scholar 

  30. Huisman, T. H. J., Brandt, G., and Wilson, J. B., J. Biol. Chem., 243, 3637 (1968).

    Google Scholar 

  31. Huisman, T. H. J., Dozy, A. M., Wilson, J. B., Effremov, G. D., and Vaskov, B., Biochim. Biophys. Acta, 160, 467 (1968).

    CAS  PubMed  Google Scholar 

  32. Beale, D., Lehman, H., Drury, A., and Tucker, E. M., Nature, 209, 1099 (1966).

    ADS  CAS  PubMed  Google Scholar 

  33. Wilson, J. B., Brandt, G., and Huisman, T. H. J., J. Biol. Chem., 243, 3687 (1968).

    CAS  PubMed  Google Scholar 

  34. Schroeder, W. A., Shelton, J. R., Shelton, J. B., Cormick, J., and Jones, R. T., Biochemistry, 2, 992 (1963).

    CAS  PubMed  Google Scholar 

  35. Air, G. M., and Thomson, E. O. P., Austral J. Biol. Sci., 22, 1437 (1969).

    CAS  Google Scholar 

  36. Rifkin, D. B., Rifkin, M. R., and Konigsberg, W., Proc. US Nat. Acad. Sci., 55, 586 (1966).

    ADS  CAS  Google Scholar 

  37. Braunitzer, G., Best, J. S., Flamm, U., and Schrank, B., Z. Physiol. Chem., 347, 207 (1966).

    CAS  Google Scholar 

  38. Boyer, S. H., Crosby, E. F., Thurmon, T. F., Noyes, A. N., Fuller, G. F., Leslie, S. E., and Sheppard, M. K., Science, 116, 1428 (1969).

    ADS  Google Scholar 

  39. Matsuda, G., Maita, T., Ota, H., Tachiwaka, I., Tanaka, Y., Araya, A., and Nakashima, Y., Intern. J. Protein Res., 3, 41 (1971).

    Google Scholar 

  40. Ingram, V. M., and Stretton, A. O. W., Biochim. Biophys. Acta, 63, 20 (1962).

    CAS  PubMed  Google Scholar 

  41. Smith, D. B., Canad. J. Biochem., 46, 825 (1968).

    CAS  Google Scholar 

  42. Babin, D. R., Schroeder, W. A., Shelton, J. R., Shelton, J. B., and Robberson, B., Biochemistry, 5, 1297 (1966).

    CAS  PubMed  Google Scholar 

  43. Wilson, J. B., Edwards, W. C., McDaniel, M., Dobbs, M. M., and Huisman, T. H. J., Arch. Biochem. Biophys., 115, 385 (1966).

    CAS  Google Scholar 

  44. Schroeder, W. A., Shelton, J. R., Shelton, J. B., Robberson, B., and Babin, D. R., Arch. Biochem. Biophys., 120, 124 (1967).

    CAS  PubMed  Google Scholar 

  45. Huisman, T. H. J., Dasher, G. A., Moretz, W. H., Dozy, A. M., and Wilson, J. B., Biochem. J., 107, 745 (1968).

    PubMed Central  Google Scholar 

  46. Boyer, S. H., Hathaway, P., Pascasio, F., Orton, C., Bordley, J., and Naughton, M. A., Science, 153, 1539 (1966).

    ADS  CAS  PubMed  Google Scholar 

  47. Huisman, T. H. J., Adams, H. R., Dimock, M. O., Edwards, W. E., and Wilson, J. B., J. Biol. Chem., 242, 2534 (1967).

    CAS  PubMed  Google Scholar 

  48. Huber, R., Epp, O., and Formanck, H., J. Mol. Biol., 42, 59 (1969).

    Google Scholar 

  49. Briehl, R. W., J. Biol. Chem., 238, 2361 (1963).

    CAS  Google Scholar 

  50. Balani, A. S., and Barnabas, J., Nature, 205, 1019 (1965).

    ADS  Google Scholar 

  51. Balani, A. S., Ranjekar, P. K., and Barnabas, J., Comp. Physiol. Biochem., 24, 809 (1968).

    CAS  Google Scholar 

  52. Huisman, T. H. J., Wilson, J. B., and Adams, H. R., Arch. Biochem. Biophys., 121, 528 (1967).

    CAS  PubMed  Google Scholar 

  53. Ranjekar, P. K., and Barnabas, J., Indian J. Biochem., 6, 1 (1969).

    CAS  PubMed  Google Scholar 

  54. Barnicot, N. A., and Huehns, E. R., Nature, 215, 1485 (1967); Wade, P. T., Skinner, A. F., and Barnicot, N. A., Protides in Biological Fluids, 263 (Pergamon, London, 1970).

    Google Scholar 

  55. Oliver, E., and Kitchen, H., Biochim. Biophys. Acta, Res. Commun., 31, 749 (1968).

    CAS  Google Scholar 

  56. Hilse, K., and Popp, R. A., Proc. US Nat. Acad. Sci., 61, 930 (1968).

    ADS  CAS  Google Scholar 

  57. Kunkel, H. G., and Wallenius, G., Science, 122, 288 (1955).

    ADS  CAS  PubMed  Google Scholar 

  58. Kunkel, H. G., Ceppellini, R., Mueller-Eberhard, V., and Wolf, J., J. Clin. Invest., 36, 1615 (1957).

    CAS  PubMed  PubMed Central  Google Scholar 

  59. Huisman, T. H. J., Reynolds, C. A., Dozy, A. M., and Wilson, J. B., J. Biol. Chem., 240, 2455 (1965).

    CAS  PubMed  Google Scholar 

  60. Hamilton, W. J., Boyd, J. D., and Mossman, H. W., Human Embryology (Williams and Wilkins, Baltimore, 1952).

    Google Scholar 

  61. Kimura, M., Proc. US Nat. Acad. Sci., 63, 1181 (1969).

    ADS  CAS  Google Scholar 

  62. Buettner-Janusch, J., and Buettner-Janusch, V., Amer. J. Phys. Anthrop., 33, 73 (1970).

    CAS  PubMed  Google Scholar 

  63. Ohno, S., Evolution by Gene Duplication (Springer, Berlin, 1970).

    Google Scholar 

  64. Buettner-Janusch, J., and Hill, R. W., in Evolving Genes and Proteins, 167 (Academic Press, London and New York, 1965).

    Google Scholar 

  65. LeGros Clark, W. E., The Antecedents of Man (Edinburgh University Press, Edinburgh, 1959).

    Google Scholar 

  66. Buettner-Janusch, J., Buettner-Janusch, V., and Mason, G. A., Arch. Biochem. Biophys., 133, 164 (1969).

    CAS  PubMed  Google Scholar 

  67. Blombäck, B., Blombäck, M., and Grondahl, N. J., Acta Chem. Scand., 19, 1789 (1965).

    Google Scholar 

  68. Blombäck, B., Blombäck, M., Grondahl, N. J., and Holmberg, E., Arkiv. Kemi., 25, 411 (1966).

    Google Scholar 

  69. Blombäck, B., Blombäck, M., Grondahl, N. J., Guthrie, C., and Hinton, M., Acta Chem. Scand., 19, 1788 (1965); Blombäck, B., Blombäck, M., and Edman, B., Biochim. Biophys. Acta, 115, 371 (1966).

    Google Scholar 

  70. Doolittle, R. F., Glasgow, C., and Mross, G. A., Biochim. Biophys. Acta, 175, 217 (1969).

    CAS  PubMed  Google Scholar 

  71. Mross, G. A., Doolittle, R. F., and Roberts, B. F., Science, 170, 468 (1970).

    ADS  CAS  PubMed  Google Scholar 

  72. Doolittle, R. F., and Mross, G. A., Nature, 225, 643 (1970).

    ADS  CAS  PubMed  Google Scholar 

  73. Blombäck, B., and Blombäck, M., in Chemotaxonomy and Serotaxonomy, 3 (Academic Press, London and New York, 1968).

    Google Scholar 

  74. Doolittle, R. F., Schubert, D., and Schwartz, S. A., Arch. Biochem. Biophys., 118, 456 (1967).

    CAS  PubMed  Google Scholar 

  75. Mross, G. A., and Doolittle, R. F., Arch. Biochem. Biophys., 122, 674 (1967).

    CAS  Google Scholar 

  76. Doolittle, R. F., and Blombäck, B., Nature, 202, 147 (1964).

    ADS  CAS  PubMed  Google Scholar 

  77. McKenna, M. C., Ann. NY Acad. Sci., 167, 217 (1969).

    ADS  Google Scholar 

  78. Tashian, R. E., and Stroup, S. R., Biochem. Biophys. Res. Commun., 41, 1457 (1970).

    CAS  PubMed  Google Scholar 

  79. Goodman, M., Human Biol., 34, 104 (1962).

    CAS  PubMed  Google Scholar 

  80. Goodman, M., Ann. NY Acad. Sci., 102, 219 (1962).

    ADS  CAS  PubMed  Google Scholar 

  81. Goodman, M., Human Biol., 35, 377 (1963).

    CAS  PubMed  Google Scholar 

  82. Goodman, M., Primates in Med., 1, 10 (1968).

    CAS  Google Scholar 

  83. Darwin, C., The Descent of Man and Selection in Relation to Sex (Appleton, New York, 1871).

    Google Scholar 

  84. Patterson, B., Behrensmeyer, A. K., and Sill, W. D., Nature, 226, 918 (1970).

    ADS  CAS  PubMed  Google Scholar 

  85. Howell, F. C., Nature, 223, 1234 (1969).

    ADS  CAS  PubMed  Google Scholar 

  86. Simons, E. L., Nature, 221, 448 (1969).

    ADS  CAS  PubMed  Google Scholar 

  87. Leakey, L. S. B., Nature, 213, 155 (1967).

    ADS  CAS  PubMed  Google Scholar 

  88. Pilbeam, D. R., Peabody Mus. Bull. Yale, 31, (1969).

  89. Kohne, D. E., Quart. Rev. Biophys., 3, 327 (1970).

    CAS  Google Scholar 

  90. Kohne, D. E., Chison, J. A., and Hoyer, B. H., Carnegie Inst. Yr Book, 69, 488 (1971).

    Google Scholar 

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GOODMAN, M., BARNABAS, J., MATSUDA, G. et al. Molecular Evolution in the Descent of Man. Nature 233, 604–613 (1971). https://doi.org/10.1038/233604a0

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