Abstract
THE question of how skin grafts are revascularized is still not resolved1–3. In particular, it is not known whether the vessels in the vascular bed of a graft derive from the host or the donor. In what follows, we provide three independent lines of evidence which suggest that in full-thickness skin grafts, the vessels are native to the graft at least for the first several days and during the period of allograft rejection. The possibility that the endothelium in surviving allografts may eventually be replaced by cells of host genotype is important4 but outside the scope of this report.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Converse, J. M., Filler, M., and Ballantye, jun., D. L., Transplantation, 3, 22 (1965).
Haller, J. A., Rauenhorst, J., Atkins, J., and Billingham, R. E., Surg. Forum (American College of Surgeons), 17, 96 (1966).
Zarem, H. A., Surgery, 66, 392 (1969).
Billingham, R. E., Brent, L., and Medawar, P. B., Phil. Trans. Roy. Soc., 239, 357 (1956).
Lambert, P. B., Transplantation, 10, 463 (1970).
Zarem, H. A., Zweifach, B. W., and McGehee, J. M., Amer. J. Phys., 212, 1081 (1967).
Lambert, P. B., Frank, H. A., Bellman, S., and Friedman, E., Angiology, 14, 121 (1963).
Bellman, S., Velander, E., Frank, H. A., and Lambert, P. B., Transplantation, 2, 167 (1964).
Lambert, P. B., and Frank, H. A., Science, 155, 99 (1967).
Lambert, P. B., and Frank, H. A., J. Exp. Med., 132, 868 (1970).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LAMBERT, P. Vascularization of Skin Grafts. Nature 232, 279–280 (1971). https://doi.org/10.1038/232279a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/232279a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
