Abstract
SMALL lymphocytes are known to act as specific mediators of delayed hypersensitivity reactions and immunoglobulin (Ig) determinants1,2 and antigen-specific receptor sites3,4 have recently been demonstrated on the lymphocyte surface. We have investigated in guinea-pigs the numbers of circulating small lymphocytes binding tuberculin in relation to the development of delayed hypersensitivity to tuberculin during primary immunization with BCG vaccine.
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DONALD, D., BECK, J. Antigen-binding Small Lymphocytes in Delayed Hypersensitivity to Tuberculin. Nature 231, 183–184 (1971). https://doi.org/10.1038/231183a0
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DOI: https://doi.org/10.1038/231183a0
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