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Carcinogenicity of Industrial Chemicals Propylene Imine and Propane Sultone

Nature volume 230, pages 460–461 (1971)Cite this article

Abstract

PROPYLENE imine is an important chemical intermediate with a variety of applications in the production of polymers, coatings, adhesives, textiles and paper finishes. Likewise, propane sultone has many potential uses in the detergent, textile, rubber, pharmaceutical and agricultural chemical industries. Their chemical reactivity suggests that these compounds may have deleterious effects in living systems. Ethylene imine, closely related to the higher homologue, propylene imine, is known to have carcinogenic, mutagenic and teratogenic activity1–3. A preliminary report dealing with the carcinogenicity of propane sultone has appeared4.

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Authors and Affiliations

  1. Bionetics Research Laboratories Inc., 5510 Nicholson Lane, Kensington, Maryland, 20852

    B. ULLAND & M. FINKELSTEIN

  2. National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20014

    E. K. EISBURGER, J. M. RICE & J. H. WEISBURGER

Authors
  1. B. ULLAND
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  2. M. FINKELSTEIN
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  3. E. K. EISBURGER
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  4. J. M. RICE
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  5. J. H. WEISBURGER
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ULLAND, B., FINKELSTEIN, M., EISBURGER, E. et al. Carcinogenicity of Industrial Chemicals Propylene Imine and Propane Sultone. Nature 230, 460–461 (1971). https://doi.org/10.1038/230460a0

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  • DOI: https://doi.org/10.1038/230460a0

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