Abstract
THE relative importance of the pituitary gland and the uterus in controlling the lifespan of the corpus luteum in mammals has been the subject of extensive investigation. In some species, the local nature of the effect of the uterus on the corpora lutea seems to preclude the involvement of the pituitary gland in luteolysis; while on the other hand the effect of gonadal steroids on luteal regression has usually been attributed to an action at the pituitary level1. The fact that the luteolytic action of oestrogen is abolished in the hysterectomized guinea-pig2, however, reaffirms the importance of the uterus.
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BLATCHLEY, F., DONOVAN, B., POYSER, N. et al. Identification of Prostaglandin F2α in the Utero-ovarian Blood of Guinea-pig after Treatment with Oestrogen. Nature 230, 243–244 (1971). https://doi.org/10.1038/230243a0
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DOI: https://doi.org/10.1038/230243a0
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