Abstract
Nonsense fragments produced by amber and ochre mutants of the z gene of E. coli are rapidly degraded during exponential growth. Wild type β-galactosidase is stable in the same conditions.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Craven, G. R., Steers, E., and Anfinsen, C. B., J. Biol. Chem., 240, 2468 (1965).
Fowler, A. V., and Zabin, I., Science, 154, 1027 (1966).
Katze, J., Sridhara, S., and Zabin, I., J. Biol. Chem., 241, 5341 (1966).
Brown, J. L., Brown, D. M., and Zabin, I., Proc. US Nat. Acad. Sci., 53, 1139 (1967).
Fowler, A. V., and Zabin, I., J. Mol. Biol., 33, 35 (1968).
Morrison, S., and Zipser, D., J. Mol. Biol., 50, 359 (1970).
Fairbanks, jun., G., Levinthal, C., and Reeder, R. H., Biochem. Biophys. Res. Commun., 20, 343 (1965).
Goldschmidt, R. thesis, Columbia University (1970).
Shapiro, A., Viñuela, E., and Maizel, J. V., Biochem. Biophys. Res. Commun., 20, 393 (1965).
Weber, K., and Osborn, M., J. Biol. Chem., 244, 4406 (1969).
Capecchi, M. R., Proc. US Nat. Acad. Sci., 58, 1144 (1967).
Mandelstam, J., Ann. NY Acad. Sci., 102, 621 (1963).
Pine, M. J., Biochim. Biophys. Acta, 104, 439 (1965).
Pine, M. J., J. Bact., 92, 847 (1966).
Pine, M. J., J. Bact., 93, 1527 (1967).
Willets, N. S., Biochem. J., 103, 453 (1967).
Mandelstam, J., Bact. Rev., 24, 289 (1960).
Holland, J. J., and Kiehn, E. D., Proc. US Nat. Acad. Sci., 60, 1015 (1968).
Jacobson, M. F., and Baltimore, D., Proc. US Nat. Acad. Sci., 61, 77 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GOLDSCHMIDT, R. In vivo Degradation of Nonsense Fragments in E. coli. Nature 228, 1151–1154 (1970). https://doi.org/10.1038/2281151a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/2281151a0
This article is cited by
-
Intracellular proteolysis: Signals of selective protein degradation
Russian Journal of Bioorganic Chemistry (2000)
-
Physiological responses of Lactococcus lactis ML3 to alternating conditions of growth and starvation
Archives of Microbiology (1993)
-
Proteases and protein degradation inEscherichia coli
Experientia (1992)
-
Quantitative evaluation of recA gene expression in Escherichia coli
Molecular and General Genetics MGG (1982)
-
Immunological and genetic properties of Escherichia coli K12 argE mutants
Molecular and General Genetics MGG (1980)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
