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Experimental Transmission of Feline Fibrosarcoma to Cats and Dogs

Abstract

An infectious C-type feline sarcoma virus (FSV), isolated from a naturally occurring fibrosarcoma of a domestic house cat, produces fibrosarcomas in kittens and puppies and induces cell transformation in feline embryo fibroblasts. Prenatal inoculation of cat and dog foetuses is particularly effective in tumour transmission. Postnatal dogs bearing FSV induced fibrosarcomas provide antisera suitable for detecting the feline C-type RNA tumour virus antigens in the complement fixation test.

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GARDNER, M., RONGEY, R., ARNSTEIN, P. et al. Experimental Transmission of Feline Fibrosarcoma to Cats and Dogs. Nature 226, 807–809 (1970). https://doi.org/10.1038/226807a0

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