Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Gene Order of RNA Bacteriophage M12

Abstract

In vitro translation of M12 RNA nascent strands, isolated from the M12 replicative intermediate, revealed the gene order: 5′–A-protein–coat protein–replicase–3′.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Gussin, G. N., J. Mol. Biol/, 21, 435 (1966).

  2. Horiuchi, K., Lodish, H. F., and Zinder, N. D., Virology, 28, 438 (1966).

    Article  CAS  Google Scholar 

  3. Viñuela, E., Algranati, I. D., and Ochoa, S., Europ. J. Biochem., 1, 3 (1967).

    Article  Google Scholar 

  4. Viñuela, E., Algranati, I. D., Feix, G., Garwes, D., Weissmann, C., and Ochoa, S., Biochim. Biophys. Acta, 155, 558 (1968).

    Article  Google Scholar 

  5. Oeschger, M. P., and Nathans, D., J. Mol. Biol., 22, 235 (1966).

    Article  CAS  Google Scholar 

  6. Lodish, H. F., Nature, 220, 345 (1968).

    Article  ADS  CAS  Google Scholar 

  7. Lodish, H. F., Biochem. Biophys. Res. Commun., 37, 127 (1969).

    Article  CAS  Google Scholar 

  8. Spahr, P. F., and Gesteland, R. F., Proc. US Nat. Acad. Sci., 59, 876 (1968).

    Article  ADS  CAS  Google Scholar 

  9. Francke, B., and Hofschneider, P. H., J. Mol. Biol, 40, 45 (1969).

    Article  CAS  Google Scholar 

  10. Studier, F. W., J. Mol. Biol., 11, 373 (1965).

    Article  CAS  Google Scholar 

  11. Robertson, H., and Zinder, N. D., J. Biol Chem., 244, 5790 (1969).

    CAS  PubMed  Google Scholar 

  12. Martin, R. G., and Ames, B. N., J. Biol Chem., 236, 1372 (1961).

    CAS  PubMed  Google Scholar 

  13. Enger, M. D., and Kaesberg, P., J. Mol. Biol., 13, 260 (1965).

    Article  CAS  Google Scholar 

  14. Sugiyama, T., Hebert, R. R., and Hartman, K. A., J. Mol. Biol, 25, 455 (1967).

    Article  CAS  Google Scholar 

  15. Ward, R., Strand, M., and Valentine, R. C., Biochem. Biophys. Res. Commun., 30, 310 (1968).

    Article  CAS  Google Scholar 

  16. Sugiyama, T., and Nakada, D., J. Mol. Biol., 31, 431 (1968).

    Article  CAS  Google Scholar 

  17. Eggen, K., and Nathans, D., J. Mol. Biol, 39, 293 (1969).

    Article  CAS  Google Scholar 

  18. Steitz, J. A., J. Mol. Biol., 33, 923 (1968).

    Article  CAS  Google Scholar 

  19. Konings, R. N. H., and Bloemendal, H., Europ. J. Biochem., 7, 165 (1969).

    Article  CAS  Google Scholar 

  20. Capecchi, M. R., J. Mol. Biol., 21, 173 (1966).

    Article  CAS  Google Scholar 

  21. Kinard, F. E., Rev. Sci. Instrum., 28, 293 (1957).

    Article  ADS  CAS  Google Scholar 

  22. Favre, R., Boy de la Tour, E., Segré, M., and Kellenberger, E., J. Ultrastruct. Res., 13, 318 (1965).

    Article  CAS  Google Scholar 

  23. Fromageot, H. P. M., and Zinder, N. D., Proc. US Nat. Acad. Sci., 61, 184 (1968).

    Article  ADS  CAS  Google Scholar 

  24. Nichols, J. L., Nature, 225, 147 (1970).

    Article  ADS  CAS  Google Scholar 

  25. Steitz, J. A., Nature, 224, 957 (1969).

    Article  ADS  CAS  Google Scholar 

  26. Lodish, H. F., Nature, 224, 867 (1969).

    Article  ADS  CAS  Google Scholar 

  27. Friedman, S. M., and Weinstein, I. B., Biochim. Biophys. Acta, 114, 593 (1966).

    Article  CAS  Google Scholar 

  28. Dahlberg, J. E., Nature, 220, 548 (1968).

    Article  ADS  CAS  Google Scholar 

  29. Garwes, D., Sillero, A., and Ochoa, S., Biochim. Biophys. Acta, 186, 166 (1969).

    Article  CAS  Google Scholar 

  30. Nathans, D., Oeschger, M., Eggen, K., and Shimura, Y., Proc. US Nat. Acad. Sci., 56, 1844 (1966).

    Article  ADS  CAS  Google Scholar 

  31. Overby, L. R., Barlow, G. H., Doi, R. H., Jacob, M., and Spiegelman, S., J. Bact., 91, 442 (1966).

    CAS  PubMed  Google Scholar 

  32. Scott, D. W., Virology, 26, 85 (1965).

    Article  CAS  Google Scholar 

  33. Fraenkel-Conrat, H., Procedures in Nucleic Acid Research (edit. by Cantoni, G. L., and Davies, P. R.), 402 (Harper and Row, New York, 1966).

    Google Scholar 

  34. Lodish, H. F., and Robertson, H., J. Mol. Biol.,, 54, 9 (1969).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

KONINGS, R., WARD, R., FRANCKE, B. et al. Gene Order of RNA Bacteriophage M12. Nature 226, 604–607 (1970). https://doi.org/10.1038/226604a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/226604a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing