Abstract
RECENT papers by Tuffrey, Bishun and Barnes1,2 have evoked great interest, because they have challenged the hitherto conventional views on the integrity of the placental barrier to maternal cells. They first reported finding an often substantial proportion (up to 33 per cent) of cells of maternal origin in certain tissues of mice aged between 4 and 60 days, which had developed in the uterus of a foster mother after transplantation at the blastocyst stage. Subsequently, they found maternal type cells in offspring from, normal pregnancies.
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References
Tuffrey, M., Bishun, N. P., and Barnes, R. D., Nature, 221, 1029 (1969).
Tuffrey, M., Bishun, N. P., and Barnes, R. D., Nature, 224, 701 (1969).
Billington, W. D., Kirby, D. R. S., Owen, J. J. T., Ritter, M. A., Burton shaw, M. D., Evans, E. P., Ford, C. E., Gauld, I. R., and McLaren, A., Nature, 224, 704 (1969).
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SELLER, M. Lack of Porosity of the Mouse Placenta to Maternal Cells. Nature 225, 1254–1255 (1970). https://doi.org/10.1038/2251254a0
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DOI: https://doi.org/10.1038/2251254a0
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