Abstract
With isolated 30S ribosomal subunits, binding of T4 mRNA is dependent on initiation factors in the absence of formyl Met-tRNAf. Formation of the 70S–mRNA complex, however, occurs only when formyl Met-tRNA and GTP are added. Initiation factors therefore control directly 30S–mRNA interaction independent of their effect on the binding of initiator tRNA.
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GREENSHPAN, H., REVEL, M. Initiator Protein Dependent Binding of Messenger RNA to Ribosomes. Nature 224, 331–335 (1969). https://doi.org/10.1038/224331a0
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DOI: https://doi.org/10.1038/224331a0
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