Abstract
DURING the past fifty years conflicting experimental evidence has been presented on the mechanism of ventricular filling and its response to exercise1. More recently, interest has been rekindled by the advent of open heart surgery and the routine replacement of diseased mitral valves with artificial prostheses. In particular, the haemodynamic results of mitral valve replacement using ball and disk valves have provided some important evidence about the way in which the ventricle fills and suggest that normally it is inseparable from mitral valve action.
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REID, K. Mitral Valve Action and the Mode of Ventricular Filling. Nature 223, 1383–1384 (1969). https://doi.org/10.1038/2231383a0
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DOI: https://doi.org/10.1038/2231383a0
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