Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effects of Prostaglandins on Fertility in Female Rats

Abstract

PROSTAGLANDINS have a wide range of pharmacological properties1,2. Because of the large quantities of prostaglandins found in seminal fluid and the stimulatory and inhibitory effects of these substances on myometrial activity, there has been speculation on the part played by prostaglandins in the physiology of reproduction. Recent developments in methods of prostaglandin biosynthesis have made large quantities of these compounds readily available, enabling us to investigate the effects of prostaglandins on fertility.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Bergström, S., Science, 157, 382 (1967).

    Article  ADS  Google Scholar 

  2. Von Euler, U. S., Clin. Pharmacol. Ther., 9, 222 (1968).

    Article  Google Scholar 

  3. Van Dorp, D. A., Burthuis, R. K., Nugtern, D. H., and Vonkeman, H., Biochim. Biophys. Acta, 90, 204 (1964).

    Article  Google Scholar 

  4. Sanner, J., Rozek, L., and Cammarata, P., in Prostaglandin Symposium of the Worcester Foundation for Experimental Biology (edit. by Ramwell, P. W., and Shaw, J. E.), 215 (Interscience, New York, 1967).

    Google Scholar 

  5. Bergström, S., Krabisch, L., Samuelsson, B., and Sjovall, J., Acta Chem. Scand., 16, 969 (1962).

    Article  Google Scholar 

  6. Canivenc, R., and Mayer, G., Ann. d'Endocrinol., 16, 1 (1955).

    CAS  Google Scholar 

  7. Mayer, G., Meunier, J. M., and Rouault, J., CR Acad. Sci., 247, 524 (1958).

    CAS  Google Scholar 

  8. Psychoyos, A., CR Soc. Biol., 152, 918 (1958).

    CAS  Google Scholar 

  9. Barnes, L. E., and Meyer, R. K., J. Reprod. Fertil., 7, 138 (1964).

    Google Scholar 

  10. Nutting, E. F., and Sollman, P. B., Acta Endocrinol. (Kbh), 54, 8 (1968).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

NUTTING, E., CAMMARATA, P. Effects of Prostaglandins on Fertility in Female Rats. Nature 222, 287–288 (1969). https://doi.org/10.1038/222287a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/222287a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing