Abstract
THE “autoimmune” NZB/Bl strain of mice is characterized by the spontaneous occurrence of haemolytic anaemia1 and red cell autoantibodies2–4. Renal lesions are also present, and immunofluorescent techniques have shown deposits of gamma globulin in the glomerular tuft5,6, suggesting a primary autoimmune renal disorder6. We have used adoptive immunization to investigate renal lesions in NZB/Bl mice in an attempt to relate the lesions to the occurrence of red cell autoantibodies.
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BARNES, R., BERRY, C. & HOLLIDAY, J. Renal Lesions in Young Adoptively Immunized NZB/BI Mice. Nature 222, 188–190 (1969). https://doi.org/10.1038/222188a0
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DOI: https://doi.org/10.1038/222188a0
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