Abstract
WE wish to present evidence that during the development of the spinal cord, nerve fibres in their primitive unsheathed condition may degenerate. We shall also show that a site where this breakdown begins can be recognized in electron micrographs as a local herniation of the fibre, with the swelling of cytoplasmic organelles within into apparently empty vesicles, variable in form, which at first are contained within the enlarged surface membrane of the fibre. This later breaks down, discharging the contents into spaces within the embryonic cord.
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HUGHES, A., EGAR, M. & TURNER, T. Degeneration of Nerve Fibres within the Embryonic Spinal Cord. Nature 221, 579–581 (1969). https://doi.org/10.1038/221579a0
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DOI: https://doi.org/10.1038/221579a0
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