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Effects of Ethanol and Acetone on Action Potential and Inhibitory Potential of Guinea-pig Taenia Coli

Abstract

THE smooth muscle of the guinea-pig taenia coli gives a transient hyperpolarization response to an external, short pulse field stimulation. This hyperpolarization has been called the inhibitory potential, and reported as a potential which is produced by the stimulation of the intrinsic inhibitory nerve1–3. On the other hand, it has been shown that the frequency and the amplitude of the miniature endplate potential in the skeletal muscle are increased by alcohol, whereas the action potential is abolished4,5.

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References

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SUNANO, S., MIYAZAKI, E. Effects of Ethanol and Acetone on Action Potential and Inhibitory Potential of Guinea-pig Taenia Coli. Nature 221, 380–381 (1969). https://doi.org/10.1038/221380a0

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