Abstract
THE urine of normal humans contains two classes of immunoglobulins, γG-globulin and γA-globulin. These proteins exist in urine as 7SγG (refs. 1–4) and 11.-8SγA (ref. 5), as well as subunits of these proteins1,4–11. It is, however, generally accepted that 19SγM is not a normal constituent of urine, and that heavy chain fragments of γM have not been identified in normal urine. It has been reported12–14 that strenuous exercise enhances the urinary excretion of most plasma proteins, including subunits of immunoglobulins.
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POORTMANS, J. Urinary Excretion of a γM-related Substance following Muscular Exercise. Nature 221, 376–378 (1969). https://doi.org/10.1038/221376a0
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DOI: https://doi.org/10.1038/221376a0
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