Abstract
ENGINEERING techniques have shown that the apparently “healed” incised skin wound in the rat is weaker and more brittle than unwounded skin up to 5 months after the beginning of healing. Tensile strength increases with time, but there is no tendency for extensibility to recover after the first month1,2. The physical nature of the wound collagen, that is, fibre shape and weave, probably plays an important part in determining these properties3. We therefore decided to look at the structure of the wounds directly to see if this could explain the mechanical findings.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Forrester, J. C., Zederfeldt, B. H., Hunt, T. K., and Dunphy, J. E., Digest Seventh Intern. Conf. Med. and Biol. Eng., Session 27, page 370, Stockholm (1967).
Forrester, J. C., Zederfeldt, B. H., and Hunt, T. K., J. Surg. Res. (in the press).
Peacock, E. E., J. Surg. Res., 7, 433 (1967).
Hayes, T. L., Pease, R. F. W., and McDonald, L. W., Lab. Invest., 15, 1320 (1966).
Hayes, T. L., and Pease, R. F. W., in Adv. Biol. and Medical Phys., 12 (Academic Press, New York, in the press).
McDonald, L. W., Pease, R. F. W., and Hayes, T. L., Lab. Invest., 16, 532 (1967).
Gibson, T., Kenedi, R. M., and Craik, J. E., Brit. J. Surg., 52, 764 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
FORRESTER, J., HUNT, T., HAYES, T. et al. Scanning Electron Microscopy of Healing Wounds. Nature 221, 373–374 (1969). https://doi.org/10.1038/221373a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/221373a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.