Abstract
DURING collagen synthesis in mammalian cells a polypeptide precursor (protocollagen) is formed on polyribosomes. Nearly half the proline residues in protocollagen are then hydroxylated by a specific enzyme (collagen proline hydroxylase, protocollagen proline hydroxylase) to give collagen1,2.
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GOLDBERG, B., GREEN, H. Relation between Collagen Synthesis and Collagen Proline Hydroxylase Activity in Mammalian Cells. Nature 221, 267–268 (1969). https://doi.org/10.1038/221267a0
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DOI: https://doi.org/10.1038/221267a0
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