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Conformation of Ribosomal RNA of E. coli: an Infrared Analysis

Abstract

The concentration of A–U and G–C base pairs in RNA can be measured by an infrared method, which has been applied to E. coli ribosomal RNA. Results are compared with those of other spectroscopic methods.

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References

  1. Felsenfeld, G., and Hirschmann, S. Z., J. Mol. Biol., 13, 407 (1968).

    Article  Google Scholar 

  2. Fresco, J. R., Klotz, L. C., and Richards, E. G., Cold Spring Harbor Symp. Quant. Biol., 28, 83 (1963).

    Article  CAS  Google Scholar 

  3. Rich, A., and Tinoco, I., J. Amer. Chem. Soc., 82, 6409 (1960).

    Article  CAS  Google Scholar 

  4. Warshaw, M. M., and Tinoco, I., J. Mol. Biol., 20, 29 (1966).

    Article  CAS  PubMed  Google Scholar 

  5. Leng, M., and Felsenfeld, G., J. Mol. Biol., 15, 455 (1966).

    Article  CAS  PubMed  Google Scholar 

  6. Cox, R. A., and Littauer, U. Z., Biochim. Biophys. Acta, 72, 188 (1963).

    Article  CAS  PubMed  Google Scholar 

  7. Cox, R. A., Biochem. J., 98, 841 (1966).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Simpkins, H., and Richards, E. G., Biochemistry, 6, 2513 (1967).

    Article  CAS  PubMed  Google Scholar 

  9. Cantor, C. R., Jaskunas, S. R., and Tinoco, I., J. Mol. Biol., 20, 39 (1966).

    Article  CAS  PubMed  Google Scholar 

  10. Vournakis, J. N., and Scheraga, H. A., Biochemistry, 5, 2997 (1966).

    Article  CAS  PubMed  Google Scholar 

  11. Cotter, R. I., McPhie, P., and Gratzer, W. B., Nature, 216, 864 (1967).

    Article  ADS  CAS  PubMed  Google Scholar 

  12. Bush, C. A., and Scheraga, H. A., Biochemistry, 6, 3036 (1967).

    Article  CAS  PubMed  Google Scholar 

  13. Boedtker, H., Biochemistry, 6, 2718 (1967).

    Article  CAS  PubMed  Google Scholar 

  14. Cox, R. A., and Kanagalingam, K., Biochem, J., 103, 749 (1967).

    Article  CAS  Google Scholar 

  15. Miles, H. T., Biochim. Biophys. Acta, 80, 325 (1958).

    Google Scholar 

  16. Miles, H. T., and Frazier, J., Biochem. Biophys. Res. Commun., 14, 21 (1964).

    Article  CAS  PubMed  Google Scholar 

  17. Howard, F. B., Frazier, J., Lipsett, M. N., and Miles, H. T., Biochem. Biophys. Res. Commun., 17, 93 (1964).

    Article  CAS  Google Scholar 

  18. Thomas, G. J., Biopolymers (in the press).

  19. Jones, R. N., J. Amer. Chem. Soc., 74, 2681 (1952).

    Article  CAS  Google Scholar 

  20. Nirenberg, M. W., and Matthaei, J. H., Proc. US Nat. Acad. Sci., 47, 1588 (1961).

    Article  ADS  CAS  Google Scholar 

  21. Brahms, J., Maurizot, J. C., and Michelson, A. M., J. Mol. Biol., 25, 465 (1967).

    Article  CAS  PubMed  Google Scholar 

  22. Brahms, J., Maurizot, J. C., and Michelson, A. M., J. Mol. Biol., 25, 481 (1967).

    Article  CAS  PubMed  Google Scholar 

  23. Sarkar, P. K., and Yang, J. T., J. Biol. Chem., 240, 2088 (1965).

    CAS  PubMed  Google Scholar 

  24. Sarkar, P. K., and Yang, J. T., Biochemistry, 4, 1238 (1965).

    Article  CAS  Google Scholar 

Download references

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COTTER, R., GRATZER, W. Conformation of Ribosomal RNA of E. coli: an Infrared Analysis. Nature 221, 154–156 (1969). https://doi.org/10.1038/221154a0

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