Abstract
IN 1954, Chappell and Perry1 observed that swelling of mitochondria was initiated by the demasking of a latent mitochondrial ATPase. Later Lehninger and his colleagues2 demonstrated that mitochondrial contraction was accompanied by a low ATPase level. The part played by the mitochondrial ATPase during swelling is, however, as yet unexplained.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Chappell, J. B., and Perry, S. V., Nature, 173, 1094 (1954).
Vignais, P. M., Vignais, P. V., and Lehninger, A. L., J. Biol. Chem., 239, 2002 (1964).
Brenner-Holzach, O., and Raaflaub, J., Helv. Physiol. Acta, 12, 242 (1954).
Zimmer, G., Z. Physiol. Chem., 345, 187 (1966).
Zimmer, G., and Krieger, K., FEBS Lett., 1, 142 (1968).
Hogeboom, G. H., Methods in Enzymology (edit. by Colowick, P., and Caplan, N. O.), 1 (1955).
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).
Kielley, W. W., and Kielley, R. K., J. Biol. Chem., 200, 213 (1953).
Fiske, C. H., and Subbarow, Y., J. Biol. Chem., 66, 375 (1925).
Penefsky, H. S., and Warner, R. C., J. Biol. Chem., 240, 4694 (1965).
Schatz, G., Penefsky, H. S., and Racker, E., J. Biol. Chem., 242, 2552 (1967).
Packer, L., Utsumi, K., and Mustafa, M. G., Arch. Biochem. Biophys., 117, 381 (1966).
Cooper, C., J. Biol. Chem., 235, 1815 (1960).
Siekevitz, P., Löw, H., Ernster, L., and Lindberg, O., Biochim. Biophys. Acta, 29, 378 (1958).
Franklin, T. J., Jones, C. W., and Redfearn, E. R., Biochim. Biophys. Acta, 131, 240 (1967).
Peter, J. B., and Lee, L. D., Biochem. Biophys. Res. Commun., 28, 1053 (1967).
Höfer, M., and Pressman, B. C., Biochemistry, 5, 3919 (1966).
Harris, E. J., Catlin, G., and Pressman, B. C., Biochemistry, 6, 1360 (1967).
Blondin, G. A., and Green, D. E., Proc. US Nat. Acad. Sci., 58, 612 (1967).
Kagawa, Y., and Racker, E., J. Biol. Chem., 241, 2475 (1966).
Robinson, J. D., Arch. Biochem. Biophys., 110, 475 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ZIMMER, G., ETTE, H. & GECK, P. Correlations of ATPase Activity and ATP Levels with Structural Alterations in Rat Liver Mitochondria during Swelling. Nature 221, 1160–1162 (1969). https://doi.org/10.1038/2211160a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/2211160a0
This article is cited by
-
Scanning electron microscopy of erythrocyte ghosts prepared with and without ATP addition
Blut Zeitschrift für die Gesamte Blutforschung (1974)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
