Abstract
THE first event after the entrance of a virus DNA into the host cell is, arguably, the partial or complete transcription of the former. This presumably occurs via the DNA-dependent RNA polymerase of the host for which two templates will have to compete, the DNA of the host and that of the virus. Why does the latter prevail ? We have compared the DNA of phage T3 and the DNA of its host, E. coli B, as templates for transcription by RNA polymerase, studying the behaviour of both native and denatured DNA1,2.
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CHEONG, L., CHARGAFF, E. Native and Denatured DNA of Phage T3 and of E. coli B as Templates for RNA Polymerase. Nature 221, 1144–1146 (1969). https://doi.org/10.1038/2211144a0
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DOI: https://doi.org/10.1038/2211144a0
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