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Unexpected High Incidence of Tumours in Thymectomized Mice treated with Anti-lymphocytic Globulin and Mycobacterium leprae

Abstract

During an attempt to transmit human leprosy (Mycobacterium leprae) to mice, polyoma-type tumours arose in all mice thymectomized as adults and treated with anti-lymphocytic globulin (ALS IgG).

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GAUGAS, J., CHESTERMAN, F., HIRSCH, M. et al. Unexpected High Incidence of Tumours in Thymectomized Mice treated with Anti-lymphocytic Globulin and Mycobacterium leprae. Nature 221, 1033–1036 (1969). https://doi.org/10.1038/2211033a0

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