Abstract
IT is still uncertain whether the α-chains of a tropo-collagen macromolecule are continuous polypeptide chains or whether they consist of subunits joined by crosslinks1. One approach to the problem has been to try to identify the polyribosomal aggregates2 at which collagen proteins are assembled within cells making collagen. It might then be possible to determine the length of the polysomal mRNA from the number of ribosomes in the polysome. If the length of the mRNA is known, then the molecular weight of the protein being made at the polysome can be inferred.
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SPEAKMAN, P. Collagen-forming Polyribosomes: Size of the Collagen Precursor. Nature 219, 724–725 (1968). https://doi.org/10.1038/219724a0
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DOI: https://doi.org/10.1038/219724a0
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