Abstract
RIBOSOMES isolated from skeletal muscle of alloxan diabetic rats are only half as effective as those from normal animals in catalysing the synthesis of protein1–4. Administration of insulin to diabetic animals restores the activity of the ribosomes to normal1. The identity of the proteins the synthesis of which is regulated by insulin, however, is not known. We report here the results of preliminary experiments that bear on the problem.
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KURIHARA, K., WOOL, I. Effect of Insulin on the Synthesis of Sarcoplasmic and Ribosomal Proteins of Muscle. Nature 219, 721–724 (1968). https://doi.org/10.1038/219721a0
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DOI: https://doi.org/10.1038/219721a0
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