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Glutaraldehyde-fixed Erythrocytes for Indirect Haemagglutination with Mycoplasma

Abstract

Mycoplasma pneumoniae (Eaton agent) is an important cause of respiratory disease in adults and children1–4. Immunological response to infection can be measured by a variety of serological procedures5–7. Of these, complement fixation and indirect haemagglutination are most useful for the required differential diagnosis from viral infection, and for epidemiological studies. Both procedures have the disadvantage of requiring considerable time and the preparation of several reagents. The applicability of the indirect haemagglutination test would be greatly extended and the test made very simple if a source of antigen-coated cells were available.

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NEIMARK, H. Glutaraldehyde-fixed Erythrocytes for Indirect Haemagglutination with Mycoplasma. Nature 219, 293–294 (1968). https://doi.org/10.1038/219293a0

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