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Nuclear Sizes in a Human Diploid/Triploid Cell Culture

Abstract

THERE is good evidence that the sizes of cells and nuclei in amphibia vary in proportion to the number of chromosome sets present1. The corresponding data for mammals are, however, extremely scanty. Apart from the special problem of somatic polyploidy, there are two reports of measurements of cell size in mammalian polyploidy. Evidence has been presented that the mean nuclear areas of liver and trophoblast cells of two human triploids (a foetus and a newborn) were larger than in corresponding cells of diploid controls2; also, in rabbits, the mean diameters of erythrocytes in triploid embryos were found to be larger than those of diploid embryos3. In all cases there was considerable overlap between the sizes of diploid and triploid cells.

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MITTWOCH, U. Nuclear Sizes in a Human Diploid/Triploid Cell Culture. Nature 219, 1074–1076 (1968). https://doi.org/10.1038/2191074a0

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