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Electron Microscopy of Muscle Phosphorylase Molecules: Significance of a Rhombic Shape

Abstract

MUSCULAR energy comes from the breakdown of glycogen. This is not, however, the only reason for interest in the enzyme, muscle phosphorylase, which catalyses the first step in the reaction. The enzyme also provides one of the clearest examples of the way activity is related to change in molecular structure. Detailed accounts are available in various reviews1–3. The more pertinent facts, which have recently changed rather substantially, seem to be as follows.

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VALENTINE, R., CHIGNELL, D. Electron Microscopy of Muscle Phosphorylase Molecules: Significance of a Rhombic Shape. Nature 218, 950–953 (1968). https://doi.org/10.1038/218950c0

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